References

1 Simone JV, Cornet JA, Abildgaard CF. Acquired von Willebrand's syndrome in systemic lupus erythematosus. Blood 1968;31:806-12.
2 Ingram GIC, Kingston PJ, Leslie J, Bowie EJW. Four cases of acquired von Willebrand's syndrome. Br J Haematol 1971;21:184-99.
3 Mant MJ, Hirsh J, Gauldie J, Bienenstock J, Pineot GF, Luke KN. von Willebrand's syndrome presenting as an acquired bleeding disorder in association with a monoclonal gammopathy. Blood 1973;42:429-36.
4 Sarji KE, Stratton RD, Wagner RH, Brinkhous KM. Nature of von Willebrand Factor: a new assay and a specific inhibitor. Proc Natl Acad Sci USA 1974;71:2937-41.
5 Stratton RD, Wagner RH, Webster WP, Brinkhous KM. Antibody nature of circulating inhibitor of plasma von Willebrand factor. Proc Natl Acad Sci USA 1975;72:4167-71.
6 Handin RI, Martin V, Moloney WC. Antibody-induced von Willebrand's disease: A newly defined inhibitor syndrome. Blood 1976;48:393-405.
7 Stableforth P, Tamagnini GL, Dormandy KM. Acquired von Willebrand syndrome with inhibitors both to factor VIII clotting activity and ristocetin-induced platelet aggregation. Br J Haematol 1976;33:565-73.
8 Wautier JL, Caen JP, Rymer R. Angiodysplasia in acquired von Willebrand disease (letter). Lancet 1976;2:973
9 Wautier JL, Levy-Toledano S, Caen JP. Acquired von Willebrand's syndrome and thrombopathy in a patient with chronic lymphocytic leukemia. Scand J Haematol 1976;16:128-34.
10 Brody JI, Levison SP, Jung CJ. Sickle cell trait and hematuria associated with von Willebrand syndromes. Ann Intern Med 1977;86:529-33.
11 Gazengel C, Prieur AM, Jacques C, Buriot D, Nedellec J, Josso F. Antibody-induced von Willebrand syndrome: inhibition of VIII VWF and VIII AGN with sparing of VIII AHF by the autoantibody. Am J Hematol 1978;5:355-63.
12 Joist JH, Cowan JF, Zimmerman TS. Acquired von Willebrand's disease: Evidence for a quantitative and qualitative Factor VIII disorder. N Engl J Med 1978;298:988-91.
13 Kaywin P, Mcdonough M, Insel PA, Shattil SJ. Platelet function in essential thrombocythemia. Decreased epinephrine responsiveness associated with a deficiency of platelet ?-Adrenergic receptors. N Engl J Med 1978;299(10):505-9.
14 Rosborough TK, Swaim WR. Acquired von Willebrand's disease, platelet-release defect and angiodysplasia. Am J Med 1978;65:96-100.
15 Zettervall O, Nilsson IM. Acquired von Willebrand's disease caused by a monoclonal antibody. Acta Med Scand 1978;204:521-8.
16 Brody JI, Haidar ME, Rossman RE. A hemorrhagic syndrome in Waldenstrom macroglobulinemia secondary to immunoadsorption of factor VIII. N Engl J Med 1979;300:408-10.
17 Clough V, MacFarlane IA, OConnor J, Wood JK. Acquired von Willebrand's syndrome and Ehlers-Danlos syndrome presenting with gastro-intestinal bleeding. Scand J Haematol 1979;22:305-10.
18 McGrath KM, Johnson CA, Stuart JJ. Acquired von Willebrand disease associated with an inhibitor to factor VIII antigen and gastrointestinal telangiectasia. Am J Med 1979;67:693-6.
19 Meyer D, Frommel D, Larrieu MJ, Zimmerman TS. Selective absence of large forms of Factor VIII/von Willebrand factor in acquired von Willebrand's syndrome: Response to transfusion. Blood 1979;54:600-6.
20 Noronha PA, Hruby MA, Maurer HS. Acquired von Willebrand disease in a patient with Wilms tumor. J Pediatr 1979;95:997-9.
21 Schneider P, Tran TC, Maillard M, Bachmann F. Acquired von Willebrand's syndrome associated with malignant lymphoma. Schweiz Med Wochenschr 1979;109:1390
22 Gan TE, Sawers RJ, Koutts J. Pathogenesis of antibody-induced acquired von Willebrand Syndrome. Am J Hematol 1980;9:363-71.
23 Holland L, Adamson A, Ingram GI, Chalmers DG. Acquired von Willebrand's syndrome. Br J Haematol 1980;45:161-4.
24 Mazurier C, Parquet-Gernez A, Descamps J, Bauters F, Goudemand M. Acquired von Willebrand's syndrome in the course of Waldenstrom's disease. Thromb Haemost 1980;44:115-8.
25 Roussi JH, Houbouyan LL, Alterescu R, Franc B, Goguel AF. Acquired Von Willebrand's syndrome associated with hairy cell leukaemia. Br J Haematol 1980;46:503-6.
26 Duran-Saurez JR, Pico M, Zuazu J, Cortes M, Monasterio J, Tringiner J. Acquired von Willebrand's disease caused by a chronic granulocytic leukemia. Br J Haematol 1981;48:772
27 Lombardi R, Mannucci PM, Seghatchian MJ, Garcia VV, Coppola R. Alterations of factor VIII von Willebrand factor in clinical conditions associated with an increase in its plasma concentration. Br J Haematol 1981;49:61-8.
28 Pickering NJ, Brody JI, Barrett MJ. von Willebrand syndromes and mitral-valve prolapse: linked mesenchymal dysplasias. N Engl J Med 1981;305:131-4.
29 Srensen PJ, Dyerberg J. Acquired von Willebrand's disease. Ugeskr Laeger 1981;143:684
30 Ercoreca L, Lucia JF, Raichs A, Palomera L. Acquired Von Willebrand's disease. A case report. Sangre (Barc) 1982;27:397-406.
31 Rogers II JS, Shane SR, Jencks FS. Factor VIII activity and thyroid function. Ann Int Med 1982;97:713-6.
32 Wood GM, Losowsky MS. Angiodysplasia of the tongue with acquired von Willebrand's disease. Postgrad Med J 1982;58:37-8.
33 Gan TE, Sawers RJ, Koutts J. The possibility of an immunologic mechanism responsible for acquired von Willebrand's disease (letter). Blood 1983;61:210
34 Mannucci PM, Remuzzi G, Pusineri F, Lombardi R, Valsecchi C, Mecca G, Zimmerman TS. Deamino-8-D-arginine vasopressin (DDAVP) increases Factor VIII/von Willebrand factor and shortens the bleeding timein uremia. N Engl J Med 1983;308(1):8-12.
35 Sampson BM, Greaves M, Malia RG, Preston FE. Acquired von Willebrand's disease: demonstration of a circulating inhibitor to the factor VIII complex in four cases. Br J Haematol 1983;54:233-44.
36 Budde U, Schaefer G, Mueller N, Egli H, Dent JA, Ruggeri ZM, Zimmerman TS. Acquired von Willebrand's disease in the myeloproliferative syndrome. Blood 1984;64:981-5.
37 Mannucci PM, Mari D. Antibodies to factor VIII/von Willebrand factor in congenital and acquired von Willebrand's disease. Prog Clin Biol Res 1984;150:109-22.
38 Mannucci PM, Lombardi R, Bader R, Horellou MH, Finazzi G, Besana C, Conard J, Samama M. Studies of the Pathophysiology of Acquired von Willebrand Disease in Seven Patients with Lymphoproliferative Disorders or Benign Monoclonal Gammopathies. Blood 1984
39 Richard C, Sedano MC, Cuadrado MA, Recio M, Hermosa V, Zubizarreta A. Acquired von Willebrand's syndrome associated with hydatid disease of the spleen--disappearance after splenectomy. Thromb Haemost1984;52:90-3.
40 Fricke WA, Brinkhous KM, Garris JB, Roberts HR. Comparison of inhibitory and binding characteristics of an antibody causing acquired von Willebrand syndrome: an assay for von Willebrand factor bindingby antibody. Blood 1985;66(3):562-9.
41 Tran TC, Mannucci PM, Schneider P, Federici AB, Bachmann F. Profound alterations of the multimeric structure of von Willebrand factor in a patient with malignant lymphoma. Br J Haematol 1985;61:307-14.
42 Bovill EG, Ershler WB, Golden EA, Tindle BH, Edson JR. A human myeloma-produced monoclonal protein directed against the active subpopulation of von Willebrand factor. Am J Clin Pathol 1986;85:115-23.
43 Budde U, Dent JA, Berkowitz SD, Ruggeri ZM, Zimmerman TS. Subunit composition of plasma von Willebrand factor in patients with the myeloproliferative syndrome. Blood 1986;68(6):1213-7.
44 Gill JC, Wilson AD, Endres-Brooks J, Montgomery RR. Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects. Blood 1986;67(3):758-61.
45 Lopez Fernandez MF, Lopez-Berges C, Martin R, Nieto J, del Rio F, Lopez-Borrasca A, Battle J. Unique multimeric pattern of von Willebrand factor in a patient with benign monoclonal gammopathy. ScandJ Haematol 1986;36:302-8.
46 Mohri H. Acquired von Willebrand disease and storage pool disease in chronic myelocytic leukemia. Am J Hematol 1986;22:391-401.
47 Takahashi H, Tatewaki W, Nagayama R, Hanano M, Wada K, Shibata A. Acquired and congenital von Willebrand factor abnormalities in congenital cardiac defects (letter). Thromb Haemost 1986;56:111
48 Takahashi H, Nagayama R, Tanabe Y, Satoh K, Hanano M, Mito M, Shibata A. DDAVP in acquired von Willebrand syndrome associated with multiple myeloma. Am J Hematol 1986;22:421-9.
49 Ball J, Malia RG, Greaves M, Preston FE. Demonstration of abnormal factor VIII multimers in acquired von Willebrand's disease associated with a circulating inhibitor. Br J Haematol 1987;65:95-100.
50 Bracey AW, Wu AHB, Aceves J, Chow T, Carlile S, Hoots WK. Platelet dysfunction associated with Wilms tumor and Hyaluronic acid. Am J Hematol 1987;24:247-57.
51 Dalton RG, Dewar MS, Savidge GF, Kernoff PBA, Matthews KB, Greaves M, Preston FE. Hypothyroidism as a cause of acquired von Willebrand's disease. Lancet 1987;1:1007-9.
52 Mannucci PM, Lombardi R, Lattuada A, Perticucci E, Valsecchi R, Remuzzi G. Supranormal von Willebrand factor multimers in scleroderma. Blood 1987;73(6):1586-91.
53 Mohri H, Noguchi T, Kodama F, Itoh A, Ohkubo T. Acquired von Willebrand disease due to inhibitor of human myeloma protein specific for von Willebrand factor. Am J Clin Pathol 1987;87:663-8.
54 Mohri H. Acquired von Willebrand Disease in patients with Polycythemia Rubra Vera. Am J Hematol 1987;26:135-46.
55 Raman BKS, Sawdyk M, Saeed M. Essential thrombocythemia with acquired von Willebrand's Disease. Am J Clin Pathol 1987;88:102-6.
56 Sanfelippo MJ, Suberviola PD, Geimer NF. Development of a von Willebrand-like syndrome after prolonged use of hydroxyethyl starch. Am J Clin Pathol 1987;88(5):653-5.
57 Silberstein LE, Abraham J, Shattil SJ. The efficacy of intensive plasma exchange in acquired von Willebrand's disease. Transfusion 1987;27:234-7.
58 Smith SR, Auger MJ. Hypothyroidism and von Willebrand's disease (letter). Lancet 1987;1:1314
59 Delannoy A, Saillez AC. High-dose intravenous gammaglobulin for acquired von Willebrand's disease (letter). Br J Haematol 1988;70:387
60 Goudemand J, Samor B, Caron C, Jude B, Gosset D, Mazurier C. Acquired type II von Willebrand's disease: Demonstration of a complexed inhibitor of the von Willebrand factor-platelet interaction and response to treatment. Br J Haematol 1988;68:227-33.
61 Macik BG, Gabriel DA, White GC, High K, Roberts HR. The use of high-dose intravenous gamma-globulin in acquired von Willebrand syndrome. Arch Pathol Lab Med 1988;112:143-6.
62 Tatewaki W, Takahashi H, Hanano M, Shibata A. Multimeric composition of plasma von Willebrand Factor in chronic myelocytic leukaemia. Thromb Res 1988;52:23-32.
63 Woodlock TJ, Francis CW, Rowe JM, Brown MJ, Marder VJ. Prolonged remission after life-threatening gastrointestinal hemorrhage from coexistent angiodysplasia and acquired bleeding diathesis. Am J Hematol 1988;27:125-31.
64 Yoshida H, Arai K, Wakashin M. Development of acquired von Willebrand's disease after mixed connective tissue disease. Am J Med 1988;85:445-6.
65 Castaman G, Rodeghiero F, Di Bona E, Ruggeri M. Clinical effectiveness of desmopressin in a case of acquired von Willebrand's syndrome associated with benign monoclonal gammopathy. Blut 1989;58:211-3.
66 Drouin J, Lillicrap DP, Izaguirre CA, Sutherland M, Windsor S, Benford K, Hoogendorn H, Giles AR. Absence of a bleeding tendency in severe acquired von Willebrand's disease. The role of platelet von Willebrand factor in maintaining normal hemostasis. Am
67 Uehlinger J, Rose E, Aledort LM, Lemer R. Successful treatment of an acquired von Willebrand factor antibody by extracorporeal immunoadsorption (letter). N Engl J Med 1989;320:254-5.
68 Weinstein MJ, Blanchard R, Moake JL, Vosburgh E, Moise K. Fetal and neonatal von Willebrand factor (vWF) is unusually large and similar to the vWF in patients with thrombotic thrombocytopenic purpura.Br J Haematol 1989;72:68-72.
69 Benson PJ, Peterson LC, Hasegawa DK, Smith CM. Abnormality of von Willebrand factor in patients with hemoglobin E-?o thalassemia. A J C P 1990;93(3):395-9.
70 Kreuz W, Linde R, Funk M, Meyer-Schrod R, Foll E, Nowak-Gottl U, Jacobi G, Vigh Zs, Scharrer I. Induction of von Willebrand disease type I by valproic acid. Lancet 1990;335:1350-1.
71 Pasi KJ, Enayat MS, Horrocks PM, Wright AD, Hill FGH. Qualitative and quantitative abnormalities of von Willebrand antigen in patients with diabetes mellitus. Thromb Res 1990;59:581-91.
72 Richard C, Cuadrado MA, Prieto M, Batlle J, Lopez Fernandez MF, Rodriguez Salazar ML, Bello C, Recio M, Santoro T, Gomez Casares MT, et al. Acquired von Willebrand Disease in multiple myeloma secondary to absorption of von Willebrand Factor by plasma cel
73 Sobel M, McNeill PM, Carlson PL, Kermode JC, Adelman B, Conroy R, Marques D. Heparin inhibition of von Willebrand factor-dependent platelet function in vitro and in vivo. J Clin Invest 1991;87:1787-93.
74 Carter C, Boughton BJ. Acquired von Willebrand's disease in Myeloproliferative Syndrome:spontaneous remission during pregnancy. Tromb Haemos 1992;67(3):387-8.
75 Castaman G, Rodeghiero F, Lattuada A, Mannucci PM. Subunit composition of plasma von Willebrand factor (vWF) in two uremic patients with acquired vWF abnormalities. Thromb Haemost 1992;67(1):183
76 Castaman G, Tosetto A, Rodeghiero F. Effectiveness of high-dose intravenous immunoglobulin in a case of acquired von Willebrand syndrome with chronic melena not responsive to desmopressin and factor VIII concentrate. Am J Hematol 1992;41:132-6.
77 Conrad ME, Latour LF. Acquired von Willebrand's disease, IgE polyclonal gammopathy and griseofulvin therapy. Am J Hematol 1992;41:143
78 Coppes MJ, Zandvoort SWH, Sparling CR, Poon AO, Weitzman S, Blanchette VS. Acquired von Willebrand disease in Wilms' tumor patients. J Clin Onc 1992;10:422-7.
79 Delmer A, Horellou MH, Brechot JM, Prudent J, Potevin F, Lecrubier C, Girard-Longhini C, Samama M, Zittoun R. Acquired von Willebrand disease:correction of hemostatic defect by high-dose intravenous immunoglobulins. Am J Hematol 1992;40:151-2.
80 Eikenboom JCJ, van der Meer FJM, Bri‰t E. Acquired von Willebrand's disease due to excessive fibrinolysis. Br J Haematol 1992;81:618-20.
81 Facon T, Caron C, Courtin P, Wurtz A, Deghaye M, Bauters F, Mazurier C, Goudemand J. Acquired type II von Willebrand's disease associated with adrenal cortical carcinoma. Br J Haematol 1992;80:488-94.
82 Federici AB, Berkowitz SD, Zimmerman TS, Mannucci PM. Proteolysis of von Willebrand factor after thrombolytic agents in patients with acute myocardial infarction. Blood 1992;79(1):38-44.
83 Glaspy JA. Disturbances in hemostasis in patients with B-cell malignancies. Sem Thromb Hemost 1992;18(4):440-8.
84 Jakway JL. Acquired von Willebrand's disease. Hematol Oncol Clin North Am 1992;6:1409-19.
85 Jakway JL. Acquired von Willebrand's disease in malignancy. Sem Thromb Hemost 1992;18:434-9.
86 Murakawa M, Okamura T, Tsutsumi K, Kamura T, Shibuya T, Harada M, Niho Y. Acquired von Willebrand's disease in association with Essential Thrombocythemia: regression following treatment. Acta Haematol 1992;87:83-7.
87 O'Brien JR, Etherington MD. Heart valve stenosis and von Willebrand's factor multimers. Lancet 1992;340:616
88 Parker RI, McKeown P, Gallin JI, Gralnick HR. Absence of the largest platelet-von Willebrand multimers in a patient with lactoferrin deficiency and a bleeding tendency. Thromb Haemostas 1992;67(3):320-4.
89 Warkentin TE, Moore JC, Morgan DG. Aortic stenosis and bleeding gastrointestinal angiodysplasia: is acquired von Willebrand's disease the link? Lancet 1992;340:35-7.
90 Federici AB, Berkowitz SD, Lattuada A, Mannucci PM. Degradation of von Willebrand factor in patients with acquired clinical conditions in which there is heightened proteolysis. Blood 1993;81:720-5.
91 Fressinaud E, Meyer D. International survey of patients with von Willebrand disease and angiodysplasia. Thromb Haemostas 1993;70:546
92 Scrobohaci ML, Daniel MT, Levy Y, Marolleau JP. Expression of GpIb on plasma cells in a patient with monoclonal IgG and acquired von Willebrand disease. Br J Haematol 1993;84:471-5.
93 Soff GA, Green D. Autoantibody to von Willebrand factor in systemic lupus erythematosus. J Lab Clin Med 1993;121:424-30.
94 Arkel YS, Lynch J, Kamiyama M. Treatment of acquired von Willebrand syndrome with intravenous immunoglobulin. Thromb Haemost 1994;72:643-51.
95 Castaman G, Rodeghiero F. Acquired transitory von Willebrand syndrome with ciprofloxacin. Lancet 1994;1:492-3.
96 Hanley D, Arkel YS, Lynch J, Kamiyama M. Acquired von Willebrand's syndrome in association with a lupus-like anticoagulant corrected by intravenous immunoglobulin. Am J Hematol 1994;46:141-6.
97 van Genderen PJJ, Vink T, Michiels JJ, van't Veer MB, Sixma JJ, van Vliet HHDM. Acquired von Willebrand disease caused by an autoantibody selectively inhibiting the binding of von Willebrand factor tocollagen. Blood 1994;84(10):3378-84.
98 Attivissimo LA, Lichtman SM, Klein I. Acquired von Willebrand's syndrome causing a hemorrhagic diathesis in a patient with hypothyroidism. Thyroid 1995;5(5):399-401.
99 Castaman G, Lattuada A, Mannucci PM, Rodeghiero F. Characterization of two cases of acquired transitory von Willebrand Syndrome with ciprofloxacin: evidence for heightened proteolysis of von Willebrand factor. Am J Hematol 1995;49:83-6.
100 Castaman G, Lattuada A, Ruggeri M, Tosetto A, Mannucci PM, Rodeghiero F. Platelet von Willebrand factor abnormalities in myeloproliferative syndromes. Am J Med 1995;49:289-93.
101 Jackson N, Hashim ZA, Zainal NA, Jamaluddin N. Puerperal acquired factor VIII inhibitor causing a von Willebrand-like syndrome in a patient with anti-DNA antibodies. Singapore Med J 1995;36(2):230-1.
102 Mohri H, Tanabe J, Ohtsuka M, Yoshida M, Motomura S, Nishida S, Fujimura Y, Okubo T. Acquired von Willebrand disease associated with multiple myeloma; characterization of an inhibitor to von Willebrand factor. Bl Coag Fibrin 1995;6(6):561-6.
103 Scott JP, Vokac EA, Schroeder T, et al. The von Willebrand Factor (vWF) propolypeptide, von Willebrand factor antigen II, distinguishes von Willebrand Syndrome (AvWS) due to the decreased synthesis ofvWF from AvWS due to increased clearance of vWF. [Abs
104 van Genderen PJJ, Terpstra W, Michiels JJ, Kapteijn L, van Vliet HHDM. High-dose intravenous immunoglobin delays clearance of von Willebrand factor in acquired von Willebrand disease. Thromb Haemost1995;73(5):891-2.
105 Anderson RP, McGrath K, Street A. Reversal of aortic stenosis, bleeding gastrointestinal angiodysplasia, and von Willebrand syndrome by aortinc valve replacement. Lancet 1996;347:689-90.
106 Treib J, Haass A, Pindur G, Miyachita C, Grauer MT, Jung F, Wenzel E, Schimrigk K. Highly substituted hydroxyethyl starch (HES200/0.62) leads to type I von Willebrand syndrome after repeated administration. Haemostasis 1996;26(4):210-3.
107 Budde U, van Genderen PJJ. Acquired von Willebrand disease in patients with high platelet counts. Sem Thromb Hemost 1997;23(5):425-31.
108 Rinder MR, Richard RE, Rinder HM. Acquired von Willebrand's disease: A concise review. Am J Hematol 1997;54:139-45.
109 Tefferi A, Nichols WL. Acquired von Willebrand disease: concise review of occurrence, diagnosis, pathogenesis and treatment. Am J Med 1997;103:536-40.
110 van Genderen PJJ, van Vliet HHDM, Prins FJ, van de Moesdijk D, van Strik R, Zijlstra FJ, Budde U, Michiels JJ. Excessive prolongation of the bleeding time by aspirin in essential thrombocythemia is related to a decrease of large von Willebrand factor mul
111 Federici AB, Rand JH, Mancini V, et al. Diagnosis and therapy of Acquired von Willebrand Syndrome (AvWS): report on 211 cases of the International Registry of AvWS. [Abstract] Blood 1998;92:556a
112 Federici AB, Stabile F, Castaman G, Canciani MT, Mannucci PM. Treatment of acquired von Willebrand syndrome in patients with monoclonal gammopathy of uncertain significance: comparison of three different therapeutic approaches. Blood 1998;92(8):2707-11
113 Mohri H, Hisanaga S, Mishima A, Fujimoto S, Uezono S, Okubo T. Autoantibody inhibits binding of von Willebrand factor to glycoprotein Ib and collagen in multiple myeloma: recognition sites present onthe A1 loop and A3 domains of von Willebrand factor.
114 Mohri H, Motomura S, Kanamori H, Matsuzaki M, Watanabe S, Maruta A, Kodama F, Okubo T. Clinical significance of inhibitors in acquired von Willebrand syndrome. Blood 1998;91(10):3623-9.
115 van Genderen PJJ, Boertjes RC, van Mourik JA. Quantitative analysis of von Willebrand factor and its propeptide in plasma in acquired von Willebrand syndrome. Thromb Haemostas 1998;80(3):495-8.
116 Viallard J-F, Pellegrin JL, Vergnes C, Borel-Derlon A, Clofent-Sanchez G, Nurden AT, Leng B, Nurden P. Three cases of acquired von Willebrand disease associated with systemic lupus erythematosus. BrJ Haemat 1999;105:532-7.